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Laser Scanning Lithography for Surface Micropatterning on Hydrogels

Mariah S. Hahn, Jordan S. Miller, Jennifer L. West

Open publisher page 93 citations

Abstract

A versatile confocal-based laser scanning lithographic method for controlled, high-fidelity two-dimensional and three-dimensional surface patterning of deformable, solvated, photoactive substrates is presented (see Figure; scale bars represent 200 μm). Patterned substrates functionalized with gradients of different cell-adhesive ligands can be fabricated, providing a tool for investigating cell–biomaterial interactions and the structure–function relationships of tissues.

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What this paper is about

A versatile confocal-based laser scanning lithographic method for controlled, high-fidelity two-dimensional and three-dimensional surface patterning of deformable, solvated, photoactive substrates is presented (see Figure; scale bars represent 200 μm). Patterned substrates functionalized with gradients of different cell-adhesive ligands can be fabricated, providing a tool for investigating cell–biomaterial interactions and the structure–function relationships of tissues.

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OpenAlex reports 93 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A versatile confocal-based laser scanning lithographic method for controlled, high-fidelity two-dimensional and three-dimensional surface patterning of deformable, solvated, photoactive substrates is presented (see Figure; scale bars represent 200 μm). Patterned substrates functionalized with gradients of different cell-adhesive ligands can be fabricated, providing a tool for investigating cell–biomaterial interactions and the structure–function relationships of tissues.

Key concepts: Micropatterning, Materials science, Lithography, Nanotechnology, Self-healing hydrogels, Biomaterial, Laser scanning, Soft lithography

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