2010Breast Cancer Research and TreatmentOpen access

The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system

Eliza Wiercinska, Hildegonda P. H. Naber, Evangelia Pardali, Gabri van der Pluijm, Hans van Dam, Peter ten Dijke

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Key concepts: MMP2, MMP9, Cancer research, SMAD, Transforming growth factor, Autocrine signalling, Metastasis, Biology

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