2011•Journal of Fish BiologyRequires access

Bactericidal activity of grass carp Ctenopharyngodon idella C9-deficient serum against Aeromonas hydrophila

C. Ji, A. H. Li, Jun Xie, D. F. Zhang, J. Y. Liu

Abstract

Neutralizing complement C9 in grass carp Ctenopharyngodon idella sera with rabbit anti-C9 sera against fish complement C9, demonstrated that bactericidal activity against Aeromonas hydrophila of the C9-deficient fish sera was greatly impaired. These results indicated that the fish complement C9 plays a key role in pathogen killing through the lytic pathway.

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Key concepts: Grass carp, Aeromonas hydrophila, Biology, Lytic cycle, Pathogen, Microbiology, Complement system, Fish <Actinopterygii>