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The Association between Ankylosing Spondylitis, Acute Anterior Uveitis and HLA-B27: The Results of a Swiss Family Study

Sjef M. van der Linden, H. U. Rentsch, Lynn H. Gerber, A. Cats, H. A. Valkenburg

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Abstract

Patients with HLA-B27 positive ankylosing spondylitis (AS) in a Swiss family study developed non-granulomatous acute anterior uveitis (AAU) 11 times more often than their healthy relatives sharing the same HLA-B27 positive haplotype (4.4% versus 0.4%; p less than 0.01) during a period of 6 months.

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What this paper is about

Patients with HLA-B27 positive ankylosing spondylitis (AS) in a Swiss family study developed non-granulomatous acute anterior uveitis (AAU) 11 times more often than their healthy relatives sharing the same HLA-B27 positive haplotype (4.4% versus 0.4%; p less than 0.01) during a period of 6 months.

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OpenAlex reports 25 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Patients with HLA-B27 positive ankylosing spondylitis (AS) in a Swiss family study developed non-granulomatous acute anterior uveitis (AAU) 11 times more often than their healthy relatives sharing the same HLA-B27 positive haplotype (4.4% versus 0.4%; p less than 0.01) during a period of 6 months.

Key concepts: Ankylosing spondylitis, Medicine, HLA-B27, Uveitis, Spondylitis, Anterior uveitis, Haplotype, Human leukocyte antigen

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