2008•Bioorganic & Medicinal Chemistry LettersRequires access

DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity

Stephen P. East, Clara Bantry White, Oliver Barker, Stephanie Barker, James M. Bennett, David Brown, Edward A. Boyd, Christopher M. Brennan, Chandana Chowdhury, Ian F. Collins, Emmanuelle Convers-Reignier, Brian William Dymock, Rowena Fletcher, David J. Haydon, Mihaly Gardiner, Stuart Hatcher, P. L. Ingram, Paul Lancett, Paul N. Mortenson, Konstantinos Papadopoulos, C. Smee, Helena B. Thomaides-Brears, Heather Tye, James A. Workman, Lloyd G. Czaplewski

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Key concepts: DNA gyrase, Topoisomerase IV, DNA supercoil, Topoisomerase, Chemistry, Antibacterial activity, Stereochemistry, DNA