2007•Bioorganic & Medicinal Chemistry LettersOpen access

Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA™ (sitagliptin phosphate)

Dooseop Kim, Jennifer E. Kowalchick, Scott D. Edmondson, Anthony Mastracchio, Jinyou Xu, George J. Eiermann, Barbara Leiting, Joseph K. Wu, KellyAnn D. Pryor, Reshma A. Patel, Huaibing He, Kathryn A. Lyons, Nancy A. Thornberry, Ann E. Weber

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Key concepts: Sitagliptin, Sitagliptin Phosphate, Chemistry, Dipeptidyl peptidase, Saxagliptin, Dipeptidyl peptidase-4, Dipeptidyl peptidase-4 inhibitor, Enzyme inhibitor