The Historical Link Between Solid-Organ Transplantation, Immunosuppression, and Skin Cancer
Henry W. Randle
Abstract
Henry W. Randle
Abstract
BACKGROUND: Skin cancers are more common in organ transplant recipients than in the general population. OBJECTIVE: The objective of this study was establish the historical link between organ transplantation, immunosuppression, and the development of skin cancer. METHODS: The pertinent literature in cutaneous oncology and transplantation is reviewed. RESULTS: There is a historical link between organ transplants, immunosuppression, and the subsequent development of skin cancers. CONCLUSIONS: Organ transplant recipients have more skin cancer than those in the general population and this is temporally related to their degree of immunosuppression.
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BACKGROUND: Skin cancers are more common in organ transplant recipients than in the general population. OBJECTIVE: The objective of this study was establish the historical link between organ transplantation, immunosuppression, and the development of skin cancer. METHODS: The pertinent literature in cutaneous oncology and transplantation is reviewed. RESULTS: There is a historical link between organ transplants, immunosuppression, and the subsequent development of skin cancers. CONCLUSIONS: Organ transplant recipients have more skin cancer than those in the general population and this is temporally related to their degree of immunosuppression.
Key concepts: Immunosuppression, Organ transplantation, Medicine, Skin cancer, Transplantation, Population, Cancer, Solid organ