Advantages of Pyridostigmine Bromide (Mestinon) and Edrophonium Chloride (Tensilon) in the Treatment of Transitory Myasthenia Gravis in the Neonatal Period

THIS paper emphasizes the value of recognizing the symptoms of myasthenia gravis, so that appropriate treatment may be given to save the lives of these newborn infants whose mothers have myasthenia gravis. The occurrence of transitory myasthenia gravis in a considerable number of the offspring of women with myasthenia gravis has been described by several authors.1 , 2 In a review of this disease Kibrick3 adds 6 cases to those previously reported.Treatment of such infants by neostigmine (Prostigmin) has been reported as being generally satisfactory, but has not been ideal as evidenced by the fact that some of the babies thus . . .