2014•PsychopharmacologyOpen access

11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors

Zi-Wei Chen, Cunde Wang, Kathiresan Krishnan, Brad Manion, Randy Hastings, John Bracamontes, Amanda Taylor, Megan Eaton, Charles F. Zorumski, Joseph H. Steinbach, Gustav Akk, Steven Mennerick, Douglas F. Covey, Alex S. Evers

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Key concepts: Neuroactive steroid, GABAA receptor, Allopregnanolone, Pregnanolone, Chemistry, Allosteric regulation, Receptor, GABAA-rho receptor