1986•Journal of Clinical Biochemistry and NutritionOpen access
Determination by the SRID Method of Normal Values of Serum Apolipoproteins (A-I, A-II, B, C-II, C-III, and E) in Normolipidemic Healthy Japanese Subjects
Yuichiro Goto, Yasuo Akanuma, Yutaka Harano, Yoshiya HATA, Hiroshige Itakura, Goro Kajiyama, M Kawade, Shunichi KOGA, Fumio Kuzuya, Yoshisuke Maruhama, Yūji Matsuzawa, Atsushi Murai, Toshio Murase, Chikayuki NAITO, Tsuguhiko NAKAI, Akio Noma, Yasushi Saitoh, Junichi Sasaki, Nozomu Takeuchi, Hiromitsu TAMACHI, Haruo UZAWA, Akira Yamamoto, Seiichiro Yamazaki, Tadao Yasugi, Susumu Yukawa
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Abstract
The normal levels of apolipoproteins in Japanese were investigated by the single radial immunodiffusion method. No differences were seen between the males and females in the apolipoprotein A-I, B, and C-III levels. However, the levels of apolipoproteins A-II and C-II were higher in the males, while that of apolipoprotein E was higher in the females. These differences were statistically significant. Except for apolipoprotein E, the apolipoprotein levels tended to increase with age more in the females than in the males. The apolipoprotein E level showed a statistically significant positive correlation not only with the total cholesterol level but also with the high density lipoprotein-cholesterol level.
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