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2009•Biochemical and Biophysical Research CommunicationsOpen access

Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells

Xiao‐Nan Li, Yuanyuan Rong, Mei Zhang, Xing Li Wang, Scott A. LeMaire, Joseph Stapleton Coselli, Yun Zhang, Ying H. Shen

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Key concepts: TXNIP, Thioredoxin-Interacting Protein, Thioredoxin, FOXO1, MAPK/ERK pathway, Oxidative stress, p38 mitogen-activated protein kinases, Intracellular

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Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells — Research Paper | ScholarLens