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Non‐Chromaffin Cell Constituents of the Adrenal Medulla are Detrimental to the Survival of Grafted Adrenal Chromaffin Cells: Studies in Rats and Non‐Human Primates

Sherry B. Schueler, John D. Ortega, Jacqueline Sagen, Jeffrey H. Kordower

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Abstract

The initial rationale for using adrenal chro- maffin cells in transplantation experiments was to provide a paraneural source of dopamine to replenish the dopamine insufficiency created in animal models of parkinsonism and idiopathic Parkinson's disease.Intraventricular transplants

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The initial rationale for using adrenal chro- maffin cells in transplantation experiments was to provide a paraneural source of dopamine to replenish the dopamine insufficiency created in animal models of parkinsonism and idiopathic Parkinson's disease.Intraventricular transplants

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Available abstract

The initial rationale for using adrenal chro- maffin cells in transplantation experiments was to provide a paraneural source of dopamine to replenish the dopamine insufficiency created in animal models of parkinsonism and idiopathic Parkinson's disease.Intraventricular transplants

Key concepts: Adrenal medulla, Chromaffin cell, Dopamine, Parkinsonism, Transplantation, Endocrinology, Adrenal insufficiency, Medicine

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Non‐Chromaffin Cell Constituents of the Adrenal Medulla are Detrimental to the Survival of Grafted Adrenal Chromaffin Cells: Studies in Rats and Non‐Human Primates — Research Paper | ScholarLens