2009•OncologyRequires access

Glial Fibrillary Acidic Protein in Brain Tumors

Eduardo Luévano, Martha Tena, Alejandra Zamora, Julio Sotelo

Abstract

Glial fibrillary acidic protein has been widely used in neurobiology and neuropathology as a specific marker for normal and abnormal astrocytes. Here, we report the immunostaining of 107 brain tumors and controls using an antiserum against glial fibrillary acidic protein. Selection of astroglia-derived tumors was easy and of high accuracy. Pattern of staining and usefulness of the method are described.

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Key concepts: Glial fibrillary acidic protein, GFAP stain, Immunostaining, Pathology, Neuropathology, Staining, Biology, Antiserum