1996Journal of Equine ScienceOpen access

Nucleotide Sequences of Open Reading Frames 1,24 and 71 of an Attenuated Equine Herpesvirus-1.

Rikio KIRISAWA, Tsutomu Kobayashi, Y Kawakami, Hiroshi Iwai

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Abstract

The nucleotide sequences of three open reading frames (ORFs), 1, 24 (partial) and 71, of an attenuated equine herpesvirus-1 strain, BK343, and its parent virulent strain HH1 were determined. In ORF1 of BK343, reiterated sequences of 299 bp were inserted and affected the reading frames of ORF1. The ORFs 24 and 71 of BK343 contained a different number of copies of repeat sequences, but this did not affect the reading frames of both ORFs. In addition, the ORF71 of BK343 had two point mutations, which affected the amino acid sequences.

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The nucleotide sequences of three open reading frames (ORFs), 1, 24 (partial) and 71, of an attenuated equine herpesvirus-1 strain, BK343, and its parent virulent strain HH1 were determined. In ORF1 of BK343, reiterated sequences of 299 bp were inserted and affected the reading frames of ORF1. The ORFs 24 and 71 of BK343 contained a different number of copies of repeat sequences, but this did not affect the reading frames of both ORFs. In addition, the ORF71 of BK343 had two point mutations, which affected the amino acid sequences.

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Available abstract

The nucleotide sequences of three open reading frames (ORFs), 1, 24 (partial) and 71, of an attenuated equine herpesvirus-1 strain, BK343, and its parent virulent strain HH1 were determined. In ORF1 of BK343, reiterated sequences of 299 bp were inserted and affected the reading frames of ORF1. The ORFs 24 and 71 of BK343 contained a different number of copies of repeat sequences, but this did not affect the reading frames of both ORFs. In addition, the ORF71 of BK343 had two point mutations, which affected the amino acid sequences.

Key concepts: ORFS, Open reading frame, Genetics, Reading (process), Biology, Strain (injury), Point mutation, Nucleic acid sequence

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Nucleotide Sequences of Open Reading Frames 1,24 and 71 of an Attenuated Equine Herpesvirus-1. — Research Paper | ScholarLens