2007•Annals of the New York Academy of SciencesRequires access

The Molecular and Cellular Aspects of Arthritis Due to Alphavirus Infections

Nestor E. Rulli, Julian V. Melton, Anja Wilmes, Gary Ewart, Suresh Mahalingam

Abstract

Alphaviruses such as the Sindbis-group viruses, Scandinavian Ockelbo virus, the African Asian chikungunya virus, the African O'nyong-nyong virus, the South American Mayaro virus, and the Australasian Barmah Forest and Ross River viruses, are commonly associated with outbreaks of acute and persistent arthritis and arthralgia in humans. The mechanisms by which these viruses cause arthritis/arthralgia are poorly understood. This chapter summarizes our current understanding of viral arthritides using our newly developed mouse model of Ross River virus-induced joint and muscle inflammation.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 80 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Alphavirus, Alphavirus infection, Ross River virus, Sindbis virus, Chikungunya, Virology, Virus, Togaviridae