1988American Journal of HematologyRequires access

Durable response to etoposide‐loaded platelets in refractory immune thrombocytopenic purpura: A case report

Lucille Wood, Peter Jacobs

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Abstract

A 23-year-old female presented with widespread purpura and ecchymoses as a result of immune thrombocytopenia which was refractory to corticosteroids, splenectomy, and immunosuppressive agents. In view of the extent and serious nature of her bleeding, salvage therapy with etoposide-loaded platelets was undertaken, which was associated with a lasting complete remission.

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A 23-year-old female presented with widespread purpura and ecchymoses as a result of immune thrombocytopenia which was refractory to corticosteroids, splenectomy, and immunosuppressive agents. In view of the extent and serious nature of her bleeding, salvage therapy with etoposide-loaded platelets was undertaken, which was associated with a lasting complete remission.

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Available abstract

A 23-year-old female presented with widespread purpura and ecchymoses as a result of immune thrombocytopenia which was refractory to corticosteroids, splenectomy, and immunosuppressive agents. In view of the extent and serious nature of her bleeding, salvage therapy with etoposide-loaded platelets was undertaken, which was associated with a lasting complete remission.

Key concepts: Thrombocytopenic purpura, Platelet, Refractory (planetary science), Splenectomy, Etoposide, Medicine, Immune system, Purpura (gastropod)

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