Alterations in serum electrolyte levels after dimethoate exposure and recovery in the freshwater air-breathing catfish , Heteropneustes fossilis (Bloch)
Vijai Krishna Das, Avinash Malviya, Rakesh Kumar Pandey
Abstract
Vijai Krishna Das, Avinash Malviya, Rakesh Kumar Pandey
Abstract
Dimethoate, a moderately toxic insecticide, has a wide range of agricultural and domestic applications. Like other organophosphates, dimethoate has anticholinesterase activity. Fish are non-target organisms, inadvertently exposed to pesticides and their metabolic products. The present study includes short-term (96 h) and long-term (36 d) effects of dimethoate exposure on some serum electrolytes Ca2+, Mg2+, and Pi in the freshwater air-breathing catfish Heteropneustes fossilis. The concentration of dimethoate for short-term exposure was 2.24 mg L−1 (75% of 96 h LC50) and for long-term exposure 0.75 mg L−1 (25% of 96 h LC50). The study includes the recovery pattern in serum electrolytes after placing the fish in pesticide-free water. Fish show hypocalcemia, hypermagnesemia, and hyperphosphatemia after short-term and long-term exposure to dimethoate. When placed in pesticide-free water, these electrolytes exhibit recovery towards normalization, indicating significant (p < 0.05) recovery.
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Dimethoate, a moderately toxic insecticide, has a wide range of agricultural and domestic applications. Like other organophosphates, dimethoate has anticholinesterase activity. Fish are non-target organisms, inadvertently exposed to pesticides and their metabolic products. The present study includes short-term (96 h) and long-term (36 d) effects of dimethoate exposure on some serum electrolytes Ca2+, Mg2+, and Pi in the freshwater air-breathing catfish Heteropneustes fossilis. The concentration of dimethoate for short-term exposure was 2.24 mg L−1 (75% of 96 h LC50) and for long-term exposure 0.75 mg L−1 (25% of 96 h LC50). The study includes the recovery pattern in serum electrolytes after placing the fish in pesticide-free water. Fish show hypocalcemia, hypermagnesemia, and hyperphosphatemia after short-term and long-term exposure to dimethoate. When placed in pesticide-free water, these electrolytes exhibit recovery towards normalization, indicating significant (p < 0.05) recovery.
Key concepts: Dimethoate, Heteropneustes fossilis, Freshwater fish, Catfish, Pesticide, Toxicology, Chemistry, Phosphamidon