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2012•Developmental BiologyOpen access

Limb anterior–posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3

Megan Bowers, Liane Eng, Zhimin Lao, Rowena K. Turnbull, Xiaozhong Bao, Elyn Riedel, Susan Mackem, Alexandra L. Joyner

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Key concepts: GLI3, GLI2, Biology, Limb development, GLI1, Zone of polarizing activity, Repressor, Hedgehog signaling pathway

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