In vitro emergence of quinolone-resistant mutants of Escherichia coli, Enterobacter cloacae, and Serratia marcescens
Masato Watanabe, Y Kotera, K Yosue, Mikako Inoue, Satoshi Mitsuhashi
Abstract
Masato Watanabe, Y Kotera, K Yosue, Mikako Inoue, Satoshi Mitsuhashi
Abstract
Norfloxacin- and ciprofloxacin-resistant mutants of several Enterobacter cloacae and Serratia marcescens isolates occurred at frequencies of greater than or equal to 10(-7)/CFU, which were higher than those of Escherichia coli isolates, in accordance with the increasing emergence of less-susceptible or resistant strains in clinical isolates of E. cloacae and S. marcescens.
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Norfloxacin- and ciprofloxacin-resistant mutants of several Enterobacter cloacae and Serratia marcescens isolates occurred at frequencies of greater than or equal to 10(-7)/CFU, which were higher than those of Escherichia coli isolates, in accordance with the increasing emergence of less-susceptible or resistant strains in clinical isolates of E. cloacae and S. marcescens.
Key concepts: Serratia marcescens, Enterobacter cloacae, Norfloxacin, Microbiology, Escherichia coli, Ciprofloxacin, Enterobacteriaceae, Biology