1963•Endocrinologia JaponicaOpen access

PROLACTIN SECRETION OF RAT ANTERIOR PITUITARY CULTIVATED IN VITRO

Takashi Kobayashi, Takuro Kobayashi, TOMONORI KIGAWA, Masahiko Mizuno, YOSHIHIKO AMENOMORI

Abstract

The rat anterior pituitary was cultivated by means of organ culture technique. The prolactin secretion in this gland was maintained or rather accelerated during 12 days cultivation. This means that the rat anterior pituitary can secrete prolactin under complete deprivation of hypothalamic control. Gonadotropin secretion was declined under the same culture condition.

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Key concepts: Prolactin, Anterior pituitary, Endocrinology, Internal medicine, Secretion, Prolactin cell, Organ culture, Pituitary gland