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2009•Bioscience Biotechnology and BiochemistryRequires access

Identification and Characterization of an Ecl1-Family Gene inSaccharomyces cerevisiae

Kenko Azuma, Hokuto Ohtsuka, Satoka Mita, Hiroshi Murakami, Hirofumi Aiba

Open publisher page 19 citations

Abstract

We found that YGR146C of Saccharomyces cerevisiae encodes a functional homolog of Ecl1 that is involved in the chronological lifespan of Schizosaccharomyces pombe. When YGR146C is overexpressed, it extends the viability of wild-type S. cerevisiae cells after entry into the stationary phase, as in the case of Ecl1. We propose that Ecl1 family proteins are novel regulatory factors involved in chronological lifespan among yeasts.

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What this paper is about

We found that YGR146C of Saccharomyces cerevisiae encodes a functional homolog of Ecl1 that is involved in the chronological lifespan of Schizosaccharomyces pombe. When YGR146C is overexpressed, it extends the viability of wild-type S. cerevisiae cells after entry into the stationary phase, as in the case of Ecl1. We propose that Ecl1 family proteins are novel regulatory factors involved in chronological lifespan among yeasts.

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OpenAlex reports 19 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

We found that YGR146C of Saccharomyces cerevisiae encodes a functional homolog of Ecl1 that is involved in the chronological lifespan of Schizosaccharomyces pombe. When YGR146C is overexpressed, it extends the viability of wild-type S. cerevisiae cells after entry into the stationary phase, as in the case of Ecl1. We propose that Ecl1 family proteins are novel regulatory factors involved in chronological lifespan among yeasts.

Key concepts: Schizosaccharomyces pombe, Saccharomyces cerevisiae, Gene, Biology, Yeast, Genetics, Identification (biology), Gene family

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Identification and Characterization of an Ecl1-Family Gene inSaccharomyces cerevisiae — Research Paper | ScholarLens