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1971•The Journal of Clinical Endocrinology & MetabolismRequires access

Probable Sleep Dependency of Diurnal Rhythm of Plasma Growth Hormone Response to Hypoglycemia

Koji Nakagawa

Open publisher page 8 citations

Abstract

No difference was found in plasma growth hormone (GH) responses to insulin-induced hypoglycemia started at 10 am and 10 pm. The GH responses to insulin injected after the onset of sleep were remarkably lower than those while awake. These results seem to indicate that the apparent diurnal rhythm in response to insulin-induced hypoglycemia is not a function of time, but secondarily of a phenomenon of sleep.

About this research paper

What this paper is about

No difference was found in plasma growth hormone (GH) responses to insulin-induced hypoglycemia started at 10 am and 10 pm. The GH responses to insulin injected after the onset of sleep were remarkably lower than those while awake. These results seem to indicate that the apparent diurnal rhythm in response to insulin-induced hypoglycemia is not a function of time, but secondarily of a phenomenon of sleep.

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OpenAlex reports 8 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

No difference was found in plasma growth hormone (GH) responses to insulin-induced hypoglycemia started at 10 am and 10 pm. The GH responses to insulin injected after the onset of sleep were remarkably lower than those while awake. These results seem to indicate that the apparent diurnal rhythm in response to insulin-induced hypoglycemia is not a function of time, but secondarily of a phenomenon of sleep.

Key concepts: Internal medicine, Endocrinology, Hypoglycemia, Circadian rhythm, Plasma glucose, Insulin, Sleep (system call), Rhythm

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