Inhibition of Cryptococcus Neoformans by Pseudomonas Aeruginosa
C. H. Teoh-Chan, P. Y. Chau, M. H. Ng, Patricia Wong
Abstract
C. H. Teoh-Chan, P. Y. Chau, M. H. Ng, Patricia Wong
Abstract
Pseudomonas aeruginosa was found to produce a factor or factors that inhibited Cryptococcus neoformans and appeared to be extracellular because the anti-C. neoformans activity was readily demonstrable in medium after the removal and killing of Pseudomonas organisms. Production of the inhibitor material was greatest in DST Agar after prolonged incubation and was reduced in the presence of glucose. A part of the inhibitory material was found to be chromatographically distinct from pyocyanin.
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Pseudomonas aeruginosa was found to produce a factor or factors that inhibited Cryptococcus neoformans and appeared to be extracellular because the anti-C. neoformans activity was readily demonstrable in medium after the removal and killing of Pseudomonas organisms. Production of the inhibitor material was greatest in DST Agar after prolonged incubation and was reduced in the presence of glucose. A part of the inhibitory material was found to be chromatographically distinct from pyocyanin.
Key concepts: Cryptococcus neoformans, Pseudomonas aeruginosa, Pyocyanin, Microbiology, Extracellular, Agar, Incubation, Cryptococcus