2007•OncogeneOpen access

Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function

Michael Markey, Jacqueline Bergseid, Emily E. Bosco, Kristy R. Stengel, Hongwei Xu, Christopher N. Mayhew, Sandy Schwemberger, Wesley A. Braden, Yong Jiang, George F. Babcock, Anil G. Jegga, Bruce J. Aronow, Michael F. Reed, J Y J Wang, Erik S. Knudsen

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Key concepts: Biology, E2F, Retinoblastoma protein, Carcinogenesis, Retinoblastoma, Downregulation and upregulation, E2F1, Regulation of gene expression