2003•Biochemical Society TransactionsRequires access

DNA replication in the hyperthermophilic archaeon Sulfolobus solfataricus

I. Dionne, Nicholas P. Robinson, Adam McGeoch, Victoria Marsh, A. Reddish, Stephen D. Bell

Abstract

Studies of the DNA-replication machinery of Archaea have revealed striking similarities to that of eukaryotes. Indeed, it appears that in most cases Archaea possess a simplified version of the eukaryotic replication apparatus. Studies of Archaea are therefore shedding light on the fundamental processes of DNA replication in both domains of life.

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Key concepts: Sulfolobus solfataricus, Archaea, Sulfolobus, DNA replication, Biology, Origin recognition complex, Eukaryotic DNA replication, Pre-replication complex