ScholarLens Back to search
1953•JAMARequires access

TREATMENT OF MELANIN HYPERPIGMENTATION

Aaron Bunsen Lerner

Open publisher page 39 citations

Abstract

Abnormal increases in melanin pigmentation of the skin have always presented a difficult problem to man because of their cosmetic and social significance. Disfiguring pigmentation of the exposed areas may have important and lasting effects on the emotional well-being of the patient. In addition, the quantity of melanin in the skin may determine the status of a person in a given society. To our knowledge little stimulus for the study of the mechanism of melanin formation has resulted from attempts to explain or modify the great variations in pigment seen in different races. Rather, the stimulus for investigation has come from observations on abnormal subjects including patients with Addison's disease, vitiligo, and hyperpigmentation of pregnancy, and from attempts to explain melanin production in plants, insects, and marine animals. As a result of these studies, much is known of the process by which the amino acid tyrosine is catalytically oxidized by

About this research paper

What this paper is about

Abnormal increases in melanin pigmentation of the skin have always presented a difficult problem to man because of their cosmetic and social significance. Disfiguring pigmentation of the exposed areas may have important and lasting effects on the emotional well-being of the patient. In addition, the quantity of melanin in the skin may determine the status of a person in a given society. To our knowledge little stimulus for the study of the mechanism of melanin formation has resulted from attempts to explain or modify the great variations in pigment seen in different races. Rather, the stimulus for investigation has come from observations on abnormal subjects including patients with Addison's disease, vitiligo, and hyperpigmentation of pregnancy, and from attempts to explain melanin production in plants, insects, and marine animals. As a result of these studies, much is known of the process by which the amino acid tyrosine is catalytically oxidized by

Why it matters

OpenAlex reports 39 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abnormal increases in melanin pigmentation of the skin have always presented a difficult problem to man because of their cosmetic and social significance. Disfiguring pigmentation of the exposed areas may have important and lasting effects on the emotional well-being of the patient. In addition, the quantity of melanin in the skin may determine the status of a person in a given society. To our knowledge little stimulus for the study of the mechanism of melanin formation has resulted from attempts to explain or modify the great variations in pigment seen in different races. Rather, the stimulus for investigation has come from observations on abnormal subjects including patients with Addison's disease, vitiligo, and hyperpigmentation of pregnancy, and from attempts to explain melanin production in plants, insects, and marine animals. As a result of these studies, much is known of the process by which the amino acid tyrosine is catalytically oxidized by

Key concepts: Melanin, Hyperpigmentation, Vitiligo, Melanosome, Tyrosine, Dermatology, Stimulus (psychology), Pigmentation disorder

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
TREATMENT OF MELANIN HYPERPIGMENTATION — Research Paper | ScholarLens