1977•British journal of surgeryRequires access

Quinacrine in the management of malignant pleural effusion

S Taylor, Nicola Hooton, A. M. Macarthur

Abstract

Twenty-five patients with malignant pleural effusion were treated with a single intrapleural dose of Quinacrine. Eighteen patients (72 per cent) had a significant response, with no reaccumulation of fluid for at least 2 months following treatment up to a maximum of 18 months in 2 patients. Seven patients (28 per cent) survived for longer than 1 year without evidence of recurrent effusion.

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Available abstract

Key concepts: Medicine, Effusion, Pleural effusion, Malignant pleural effusion, Surgery, Pleural fluid