Pharmaceuticals from cultured algae
Robert E. Schwartz, Charles F. Hirsch, David F. Sesin, James E. Flor, Michel M. Chartrain, Robert E. Fromtling, Guy H. Harris, Michael J. Salvatore, Jerrold M. Liesch, Katherine Yudin
Abstract
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Robert E. Schwartz, Charles F. Hirsch, David F. Sesin, James E. Flor, Michel M. Chartrain, Robert E. Fromtling, Guy H. Harris, Michael J. Salvatore, Jerrold M. Liesch, Katherine Yudin
Abstract
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An algae screening program, including cultured macroalgae, cultured cyanobacteria and cultured eukaryotic microalgae has been undertaken. Methods for the isolation, purification, preservation and cultivation of axenic cyanobacteria and eukaryotic cultures have been developed. Screening of these groups for biologically active components has lead to the isolation of pachydictyol and caulerpenyne from cultured macroalgae, while a series of hapalindoles and an antifungal depsipeptide have been isolated from cyanobacteria.
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An algae screening program, including cultured macroalgae, cultured cyanobacteria and cultured eukaryotic microalgae has been undertaken. Methods for the isolation, purification, preservation and cultivation of axenic cyanobacteria and eukaryotic cultures have been developed. Screening of these groups for biologically active components has lead to the isolation of pachydictyol and caulerpenyne from cultured macroalgae, while a series of hapalindoles and an antifungal depsipeptide have been isolated from cyanobacteria.
Key concepts: Cyanobacteria, Axenic, Algae, Isolation (microbiology), Biology, Microbiology, Botany, Bacteria