1995•Current BiologyOpen access

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

Peter van der Geer, Sandra E. Wiley, Venus Ka-Man Lai, Jean Paul Olivier, Gerald D. Gish, Robert M. Stephens, David R. Kaplan, Steven E. Shoelson, Tony J. Pawson

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Key concepts: GRB2, SH2 domain, Phosphotyrosine-binding domain, Autophosphorylation, Proto-oncogene tyrosine-protein kinase Src, Biology, Receptor tyrosine kinase, Signal transducing adaptor protein

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A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides — Research Paper | ScholarLens