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Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

Ed Laufer, Craig E. Nelson, Randy L. Johnson, Bruce A. Morgan, Cliff Tabin

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Key concepts: Mesoderm, Zone of polarizing activity, FGF and mesoderm formation, Apical ectodermal ridge, Limb development, Biology, Limb bud, Sonic hedgehog

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Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud — Research Paper | ScholarLens