2008•Key engineering materialsOpen access

In Vitro Evaluation of the Antimicrobial Action of Chlorhexidine Associated to Hydroxyapatite

Carlos A. Soriano de Souza, Renata Souto, Ana Paula Vieira Colombo, Antonella Rossi, Maria Helena M. Rocha‐Leão

Abstract

Chlorhexidine (CHX), a cationic antiseptic, is an antimicrobial agent with many applications. In this work, the antimicrobial action of CHX associated with hydroxyapatite (HA) was evaluated for treating oral infections. Based on the determination of MIC (6,25 mg/mL HACHX), the material showed growth inhibition of E. faecalis for up to 08 days.

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Key concepts: Chlorhexidine, Antimicrobial, Antiseptic, In vitro, Chemistry, Microbiology, Pharmacology, Dentistry