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1963•Japanese Journal of MedicineOpen access

Blood Coagulation Disorders in Hemophilia

Matsuzo Matsuoka

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Abstract

Hemophilia is a wellknown hereditary disease with sex-linked recessive transmission, but it was only a few years ago that the coagulation disorders of hemophilia were proved to be caused by a disturbance of blood thromboplastin formation. The subjects of this paper are to present the mechanism of blood thromboplastin formation and the results of recent laboratory investigations on about 12 cases of hemophilia encountered recently in our clinic. According to the laboratory findings the author should like to express how to designate hemophilia and hemophiloid state.

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What this paper is about

Hemophilia is a wellknown hereditary disease with sex-linked recessive transmission, but it was only a few years ago that the coagulation disorders of hemophilia were proved to be caused by a disturbance of blood thromboplastin formation. The subjects of this paper are to present the mechanism of blood thromboplastin formation and the results of recent laboratory investigations on about 12 cases of hemophilia encountered recently in our clinic. According to the laboratory findings the author should like to express how to designate hemophilia and hemophiloid state.

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Available abstract

Hemophilia is a wellknown hereditary disease with sex-linked recessive transmission, but it was only a few years ago that the coagulation disorders of hemophilia were proved to be caused by a disturbance of blood thromboplastin formation. The subjects of this paper are to present the mechanism of blood thromboplastin formation and the results of recent laboratory investigations on about 12 cases of hemophilia encountered recently in our clinic. According to the laboratory findings the author should like to express how to designate hemophilia and hemophiloid state.

Key concepts: Medicine, Coagulation, Thromboplastin, Coagulation Disorder, Blood coagulation factors, Partial thromboplastin time, Blood Disorder, Internal medicine

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