2012Advanced Functional MaterialsOpen access

Imaging: Chemiluminescent and Antioxidant Micelles as Theranostic Agents for Hydrogen Peroxide Associated‐Inflammatory Diseases (Adv. Funct. Mater. 19/2012)

Sujin Cho, On Hwang, Iljea Lee, Gayoung Lee, Donghyuck Yoo, Gilson Khang, Peter M. Kang, Dongwon Lee

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Abstract

Chemiluminescent micelles contain polyoxalate and fluorophore in the core and are capable of performing a peroxalate chemiluminescence reaction with hydrogen peroxide. Hydrogen peroxide is generated in large amounts during inflammatory responses. As reported by Dongwon Lee and co-workers on page 4038, diffusion of hydrogen peroxide into the interior of chemiluminescent micelles initiates the peroxalate chemiluminescence reaction and subsequent light emission, allowing the detection of inflammatory diseases.

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What this paper is about

Chemiluminescent micelles contain polyoxalate and fluorophore in the core and are capable of performing a peroxalate chemiluminescence reaction with hydrogen peroxide. Hydrogen peroxide is generated in large amounts during inflammatory responses. As reported by Dongwon Lee and co-workers on page 4038, diffusion of hydrogen peroxide into the interior of chemiluminescent micelles initiates the peroxalate chemiluminescence reaction and subsequent light emission, allowing the detection of inflammatory diseases.

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Available abstract

Chemiluminescent micelles contain polyoxalate and fluorophore in the core and are capable of performing a peroxalate chemiluminescence reaction with hydrogen peroxide. Hydrogen peroxide is generated in large amounts during inflammatory responses. As reported by Dongwon Lee and co-workers on page 4038, diffusion of hydrogen peroxide into the interior of chemiluminescent micelles initiates the peroxalate chemiluminescence reaction and subsequent light emission, allowing the detection of inflammatory diseases.

Key concepts: Hydrogen peroxide, Chemiluminescence, Materials science, Micelle, Antioxidant, Nanotechnology, Organic chemistry, Chemistry

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Imaging: Chemiluminescent and Antioxidant Micelles as Theranostic Agents for Hydrogen Peroxide Associated‐Inflammatory Diseases (Adv. Funct. Mater. 19/2012) — Research Paper | ScholarLens