2011•Biochemical and Biophysical Research CommunicationsRequires access

Correlation between time-dependent inhibition of human farnesyl pyrophosphate synthase and blockade of mevalonate pathway by nitrogen-containing bisphosphonates in cultured cells

Johanna Räikkönen, Markku Taskinen, James E. Dunford, Hannu Mönkkönen, Seppo Auriola, Jukka Mönkkönen

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Key concepts: Farnesyl pyrophosphate, Mevalonate pathway, Chemistry, Farnesyl diphosphate synthase, Isopentenyl pyrophosphate, Pyrophosphate, Enzyme, ATP synthase