2014Separation and Purification TechnologyRequires access

Optimization of enzyme-assisted negative pressure cavitation extraction of five main indole alkaloids from Catharanthus roseus leaves and its pilot-scale application

Meng Luo, Liuqing Yang, Xiaohui Yao, Fan‐Song Mu, Dongyang Zhang, Zhuoyue Song, Qi Qiao, Yujie Fu, Yuangang Zu

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Key concepts: Catharanthus roseus, Vindoline, Extraction (chemistry), Chromatography, Indole alkaloid, Chemistry, Response surface methodology, Box–Behnken design

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