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Convenient Syntheses of Racemic 2-(3-Nitrophenyl)propanoic Acid and 2-(3-Aminophenyl)propanoic Acid

Luc Grondard, Franco Manfré, Stéphane Mutti

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Abstract

2-(4-Chlorophenyl)propanoic acid 1 is transformed to 2-(4-chloro-3-nitrophenyl) propanoic acid 2 (94% yield). Acid 2 can be converted to 2-(3-nitrophenyl)propanoic acid 3 (70% yield) or to 2-(3-aminophenyl) propanoic acid 4 (80% yield).

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What this paper is about

2-(4-Chlorophenyl)propanoic acid 1 is transformed to 2-(4-chloro-3-nitrophenyl) propanoic acid 2 (94% yield). Acid 2 can be converted to 2-(3-nitrophenyl)propanoic acid 3 (70% yield) or to 2-(3-aminophenyl) propanoic acid 4 (80% yield).

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Available abstract

2-(4-Chlorophenyl)propanoic acid 1 is transformed to 2-(4-chloro-3-nitrophenyl) propanoic acid 2 (94% yield). Acid 2 can be converted to 2-(3-nitrophenyl)propanoic acid 3 (70% yield) or to 2-(3-aminophenyl) propanoic acid 4 (80% yield).

Key concepts: Propanoic acid, Chemistry, Yield (engineering), Organic chemistry, Stereochemistry, Materials science, Metallurgy

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Convenient Syntheses of Racemic 2-(3-Nitrophenyl)propanoic Acid and 2-(3-Aminophenyl)propanoic Acid — Research Paper | ScholarLens