Proof of concept, engineered cartilage tissue for cartilage injuries of knee

Sports related injuries among professional and recreational athletes are increasingly encountered and diagnosed and demand a quick return to preinjury level. At present cartilage injury cases are treated with multiple drilling, abrasion arthroplasty, mosaicplasty, autologous chondrocyte implantation (ACI) and matrix induced autologous chondrocyte implantation (MACI;). The construction of engineered cartilage tissue on a ECM (Extracellular Matrix) composite have high degree of feasibility. Since cartilage cells at the site do not grow to form new cartilage cells,tissue engineered cartilage aim at cultivating chondrocytes in vitro, and to reintroduce the engineered cultured cartilage tissue into the damaged region. To overcome the limitations that currently exist , a multidisciplinary field, in which bioengineering and medicine should emerge).