1949•Experimental Biology and MedicineRequires access

Development of Macrocytic Erythrocytes in Leukemic Subjects Receiving Folic Acid Antagonist, 4-Aminopteroylglutamic Acid (Aminopterin)

S. J. Wilson, L. Coxsey, C. Bossi

Abstract

ConclusionsIn 7 of 25 human subjects with acute leukemia treated with the folic acid antagonist 4-aminopteroylglutamic acid (aminopterin) morphologic changes developed in the circulating red blood cells consisting of a macrocytosis and anisocytosis.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Aminopterin, Folic Acid Antagonists, Anisocytosis, Macrocytosis, Folic acid, Medicine, Antagonist, Leukemia