1985•Postgraduate Medical JournalOpen access

A case of ocular toxicity to ethambutol—an idiosyncratic reaction?

AC Karnik, M. A. Al-Shamali, F. F. Fenech

Abstract

Optic neuritis, a well known adverse effect of ethambutol, is related to the dose and duration of the therapy. The patient described here developed rapidly progressive deterioration of vision after only 3 days of treatment with ethambutol. Such a case has not been reported before and it is suspected that this was an idiosyncratic reaction.

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Key concepts: Medicine, Ethambutol, Toxicity, Pharmacology, Ophthalmology, Pathology, Internal medicine, Isoniazid