1978•Journal of Experimental ZoologyRequires access

Regulation of vitellogenin synthesis in Drosophila by ecdysterone and juvenile hormone

Alfred M. Handler, John H. Postlethwait

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Abstract

Abstract The hormonal regulation of vitellogenin (Vg) synthesis in Drosophila was investigated by studying the incorporation of 3H‐leucine into hemolymph proteins of normal mature females and in isolated female abdomens either untreated or treated with solutions of a juvenile hormone analog (JHA), ecdysterone, or control solutions. It was found that the synthesis of Vg was reduced in untreated isolated abdomens and in isolated abdomens treated with control solutions, but that in isolated abdomens treated with either JHA or ecdysterone, Vg synthesis was specifically stimulated.

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Abstract The hormonal regulation of vitellogenin (Vg) synthesis in Drosophila was investigated by studying the incorporation of 3H‐leucine into hemolymph proteins of normal mature females and in isolated female abdomens either untreated or treated with solutions of a juvenile hormone analog (JHA), ecdysterone, or control solutions. It was found that the synthesis of Vg was reduced in untreated isolated abdomens and in isolated abdomens treated with control solutions, but that in isolated abdomens treated with either JHA or ecdysterone, Vg synthesis was specifically stimulated.

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Available abstract

Abstract The hormonal regulation of vitellogenin (Vg) synthesis in Drosophila was investigated by studying the incorporation of 3H‐leucine into hemolymph proteins of normal mature females and in isolated female abdomens either untreated or treated with solutions of a juvenile hormone analog (JHA), ecdysterone, or control solutions. It was found that the synthesis of Vg was reduced in untreated isolated abdomens and in isolated abdomens treated with control solutions, but that in isolated abdomens treated with either JHA or ecdysterone, Vg synthesis was specifically stimulated.

Key concepts: Ecdysterone, Juvenile hormone, Hemolymph, Vitellogenin, Vitellogenins, Endocrinology, Internal medicine, Hormone

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