In vitro 3D articular cartilage imaging using endoscopic spectral domain optical coherence tomography (SD-OCT) with a GRIN (gradient index) lens rod based probe
Tuqiang Xie, Yeh‐Chan Ahn, Zhongping Chen, George Μ. Peavy
Abstract
Tuqiang Xie, Yeh‐Chan Ahn, Zhongping Chen, George Μ. Peavy
Abstract
In this paper, a GRIN lens rod based dynamic focusing spectral domain optical coherence tomography (OCT) system with 2D scanners is presented and is used to investigate a fresh bovine joint in vitro by 3D OCT with lateral and axial resolutions of 10 μm at the speed of 8 frames/s. The experimental results demonstrate the 3D image can more efficiency and accurate to evaluate articular cartilage joint disease. It shows great potential for use in extremely compact OCT endoscopes to combine with arthroscope to image articular cartilage in vivo for diagnosis of early DJDs and simultaneously perform both 3D imaging and surface imaging in the same channel.
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In this paper, a GRIN lens rod based dynamic focusing spectral domain optical coherence tomography (OCT) system with 2D scanners is presented and is used to investigate a fresh bovine joint in vitro by 3D OCT with lateral and axial resolutions of 10 μm at the speed of 8 frames/s. The experimental results demonstrate the 3D image can more efficiency and accurate to evaluate articular cartilage joint disease. It shows great potential for use in extremely compact OCT endoscopes to combine with arthroscope to image articular cartilage in vivo for diagnosis of early DJDs and simultaneously perform both 3D imaging and surface imaging in the same channel.
Key concepts: Optical coherence tomography, Gradient-index optics, Articular cartilage, Optics, Lens (geology), Materials science, Biomedical engineering, Cartilage