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1976•Archives of Disease in ChildhoodOpen access

Pigment deposition in the reticuloendothelial system after fat emulsion infusion.

JUSTEN H. PASSWELL, Ramirez-Ortega David, Daniel Katznelson, Benjamin E. Cohen

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Abstract

In 2 infants who had received Intralipid fat emulsion as part of a total parenteral hyperalimentation regimen, a pigmented material was deposited in the macrophages of their reticuloendothelial systems. The histochemical characteristics of this pigment were similar to those seen after experimental infusion of fat emulsions. The possible implications of this finding and its effect on host resistance are briefly considered.

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What this paper is about

In 2 infants who had received Intralipid fat emulsion as part of a total parenteral hyperalimentation regimen, a pigmented material was deposited in the macrophages of their reticuloendothelial systems. The histochemical characteristics of this pigment were similar to those seen after experimental infusion of fat emulsions. The possible implications of this finding and its effect on host resistance are briefly considered.

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Available abstract

In 2 infants who had received Intralipid fat emulsion as part of a total parenteral hyperalimentation regimen, a pigmented material was deposited in the macrophages of their reticuloendothelial systems. The histochemical characteristics of this pigment were similar to those seen after experimental infusion of fat emulsions. The possible implications of this finding and its effect on host resistance are briefly considered.

Key concepts: Mononuclear phagocyte system, Fat emulsion, Medicine, Emulsion, Parenteral nutrition, Pigment, Lipid emulsion, Deposition (geology)

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