ScholarLens Back to search
1988•Journal of Analytical Atomic SpectrometryRequires access

Determination of lithium in serum and whole blood by graphite furnace atomic absorption spectrometry

Luan Shen, Xiao-quan Shan, Zheming Ni

Open publisher page 17 citations

Abstract

A method has been developed for the direct determination of lithium in serum and whole blood by graphite furnace atomic absorption spectrometry using tantalum carbide coated graphite tubes in combination with ammonium nitrate matrix modification. The maximum permissible charring temperature for lithium was raised from 1050 to 1500 °C and the lifetime of the tube was also prolonged for ca. 200 more firings using the tantalum carbide coated graphite tube compared with the conventional pyrolytic graphite coated graphite tube. Matrix interferences from chlorides present in human blood samples were eliminated using the proposed method, which has been used for the determination of lithium in serum and whole blood of normal healthy individuals.

About this research paper

What this paper is about

A method has been developed for the direct determination of lithium in serum and whole blood by graphite furnace atomic absorption spectrometry using tantalum carbide coated graphite tubes in combination with ammonium nitrate matrix modification. The maximum permissible charring temperature for lithium was raised from 1050 to 1500 °C and the lifetime of the tube was also prolonged for ca. 200 more firings using the tantalum carbide coated graphite tube compared with the conventional pyrolytic graphite coated graphite tube. Matrix interferences from chlorides present in human blood samples were eliminated using the proposed method, which has been used for the determination of lithium in serum and whole blood of normal healthy individuals.

Why it matters

OpenAlex reports 17 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

A method has been developed for the direct determination of lithium in serum and whole blood by graphite furnace atomic absorption spectrometry using tantalum carbide coated graphite tubes in combination with ammonium nitrate matrix modification. The maximum permissible charring temperature for lithium was raised from 1050 to 1500 °C and the lifetime of the tube was also prolonged for ca. 200 more firings using the tantalum carbide coated graphite tube compared with the conventional pyrolytic graphite coated graphite tube. Matrix interferences from chlorides present in human blood samples were eliminated using the proposed method, which has been used for the determination of lithium in serum and whole blood of normal healthy individuals.

Key concepts: Graphite, Graphite furnace atomic absorption, Pyrolytic carbon, Tantalum carbide, Lithium (medication), Charring, Atomic absorption spectroscopy, Tantalum

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Determination of lithium in serum and whole blood by graphite furnace atomic absorption spectrometry — Research Paper | ScholarLens