2008•Journal of Thrombosis and HaemostasisOpen access

The reversible P2Y12 antagonist cangrelor influences the ability of the active metabolites of clopidogrel and prasugrel to produce irreversible inhibition of platelet function

Natalia Dovlatova, Joseph A. Jakubowski, Atsuhiro Sugidachi, Stan Heptinstall

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Key concepts: Cangrelor, Prasugrel, P2Y12, Clopidogrel, Pharmacology, Thienopyridine, Antagonist, Platelet

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The reversible P2Y12 antagonist cangrelor influences the ability of the active metabolites of clopidogrel and prasugrel to produce irreversible inhibition of platelet function — Research Paper | ScholarLens