2002•Unpublished venueRequires access

Concepts of Combinatorial Chemistry in Process Development

Markus Eckert, Ulrich Notheis

Abstract

This chapter contains sections titled: Introduction General Subject of this Chapter Literature Process Development Overview and Definition Combinatorial Chemistry in Process Development Demands on Process Development Process Development for Different Applications Parallelization in Process Development Number of Experiments Compared with Scale of Experiment Requirements and Equipment for Parallelization in Different Development Phases Route Scouting Process Screening Process Optimization Process Characterization and Validation Requirements for Analytical Instruments Planning of Parallel Process Development Screening Strategies Experimental Design Strategies for the Selection of the Equipment Automation versus Manual Work? What is the Right Distribution and Number of Pieces of Apparatus for Different Stages? Buying Commercially Available Systems or Carrying out In-house Development? Case Studies Summary References

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Key concepts: Process (computing), Process development, Development (topology), Automation, Chemistry, Work in process, Systems engineering, Computer science