1965Acta Physiologica ScandinavicaRequires access

The Metabolism of Fatty Acids in the Rat II. Oleic Acid

Göran Göransson, Thomas Olivecrona

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Abstract

Abstract l‐C14‐Oleic acid and 9–10‐H3‐Palmitic acid in rat serum were injected intravenously to fasted and to refed male rats. The C14 and the H3 radioactivity in the tissue lipids was studied at various time intervals thereafter. The oleic acid label disappeared more rapidly from the blood FFA than did the palmitic acid label. The data indicate that oleic acid is more rapidly oxidized than palmitic acid. At short times a larger fraction of the C14 radioactivity than of the H3 radioactivity of the tissues was in the neutral lipid fraction, indicating that oleic acid is incorporated into this fraction to a larger extent than is palmitic acid.

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Abstract l‐C14‐Oleic acid and 9–10‐H3‐Palmitic acid in rat serum were injected intravenously to fasted and to refed male rats. The C14 and the H3 radioactivity in the tissue lipids was studied at various time intervals thereafter. The oleic acid label disappeared more rapidly from the blood FFA than did the palmitic acid label. The data indicate that oleic acid is more rapidly oxidized than palmitic acid. At short times a larger fraction of the C14 radioactivity than of the H3 radioactivity of the tissues was in the neutral lipid fraction, indicating that oleic acid is incorporated into this fraction to a larger extent than is palmitic acid.

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Available abstract

Abstract l‐C14‐Oleic acid and 9–10‐H3‐Palmitic acid in rat serum were injected intravenously to fasted and to refed male rats. The C14 and the H3 radioactivity in the tissue lipids was studied at various time intervals thereafter. The oleic acid label disappeared more rapidly from the blood FFA than did the palmitic acid label. The data indicate that oleic acid is more rapidly oxidized than palmitic acid. At short times a larger fraction of the C14 radioactivity than of the H3 radioactivity of the tissues was in the neutral lipid fraction, indicating that oleic acid is incorporated into this fraction to a larger extent than is palmitic acid.

Key concepts: Palmitic acid, Oleic acid, Fraction (chemistry), Metabolism, Chemistry, Fatty acid, Biochemistry, Chromatography

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