1990New England Journal of MedicineRequires access

An Error Corrected, a Conclusion Withdrawn, and a Lesson Learned

Arnold S. Relman

Open publisher page 3 citations

Abstract

In this issue is a letter from Pintor and colleagues1 that corrects the conclusions of a paper they published in the Journal nearly two years ago.2 In the earlier paper the authors reported what appeared to be a unique case of Laron dwarfism. The patient had elevated plasma levels of growth hormone combined with an abnormality in protein binding of growth hormone, which is characteristic of this type of dwarfism, but he also had a normal plasma level of insulin-like growth factor I (somatomedin C), which is not. Patients with Laron dwarfism have uniformly had low somatomedin C levels. On . . .

About this research paper

What this paper is about

In this issue is a letter from Pintor and colleagues1 that corrects the conclusions of a paper they published in the Journal nearly two years ago.2 In the earlier paper the authors reported what appeared to be a unique case of Laron dwarfism. The patient had elevated plasma levels of growth hormone combined with an abnormality in protein binding of growth hormone, which is characteristic of this type of dwarfism, but he also had a normal plasma level of insulin-like growth factor I (somatomedin C), which is not. Patients with Laron dwarfism have uniformly had low somatomedin C levels. On . . .

Why it matters

OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

In this issue is a letter from Pintor and colleagues1 that corrects the conclusions of a paper they published in the Journal nearly two years ago.2 In the earlier paper the authors reported what appeared to be a unique case of Laron dwarfism. The patient had elevated plasma levels of growth hormone combined with an abnormality in protein binding of growth hormone, which is characteristic of this type of dwarfism, but he also had a normal plasma level of insulin-like growth factor I (somatomedin C), which is not. Patients with Laron dwarfism have uniformly had low somatomedin C levels. On . . .

Key concepts: Dwarfism, Somatomedin, Medicine, Endocrinology, Growth hormone, Abnormality, Internal medicine, Hormone

Related papers

Back to paper searchBrowse research topicsOriginal source
An Error Corrected, a Conclusion Withdrawn, and a Lesson Learned — Research Paper | ScholarLens