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The Effect of Fluoride in Saliva on Remineralization of Dental Enamel in Humans

D. Lambrou, Michael Larsen, O. Fejerskov, B. Tachos

Open publisher page 35 citations

Abstract

The aim of this study was to investigate the ‘remineralizing potential’ in the mouth at certain intervals after a topical fluoride treatment. Remineralization was studied by microhardness measurements of slightly demineralized bovine enamel slabs. 4 dental students were given a topical acidulated phosphate fluoride (APF) treatment and 2, 4, 8 and 16 h after the treatment, 8 slabs were inserted and carried for 48 h. During the study, the subjects avoided other types of fluoride exposure. The statistical analysis of the microhardness changes showed a significant rehardening of the control slabs indicating remineralization from saliva. Slabs inserted 2–4 h after the fluoride treatment showed highly increased remineralization as compared to the controls, whereas those inserted 8 and 16 h after the treatment did not differ from the controls. The data are related to the fluoride concentration in saliva at various periods after APF treatments.

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What this paper is about

The aim of this study was to investigate the ‘remineralizing potential’ in the mouth at certain intervals after a topical fluoride treatment. Remineralization was studied by microhardness measurements of slightly demineralized bovine enamel slabs. 4 dental students were given a topical acidulated phosphate fluoride (APF) treatment and 2, 4, 8 and 16 h after the treatment, 8 slabs were inserted and carried for 48 h. During the study, the subjects avoided other types of fluoride exposure. The statistical analysis of the microhardness changes showed a significant rehardening of the control slabs indicating remineralization from saliva. Slabs inserted 2–4 h after the fluoride treatment showed highly increased remineralization as compared to the controls, whereas those inserted 8 and 16 h after the treatment did not differ from the controls. The data are related to the fluoride concentration in saliva at various periods after APF treatments.

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Available abstract

The aim of this study was to investigate the ‘remineralizing potential’ in the mouth at certain intervals after a topical fluoride treatment. Remineralization was studied by microhardness measurements of slightly demineralized bovine enamel slabs. 4 dental students were given a topical acidulated phosphate fluoride (APF) treatment and 2, 4, 8 and 16 h after the treatment, 8 slabs were inserted and carried for 48 h. During the study, the subjects avoided other types of fluoride exposure. The statistical analysis of the microhardness changes showed a significant rehardening of the control slabs indicating remineralization from saliva. Slabs inserted 2–4 h after the fluoride treatment showed highly increased remineralization as compared to the controls, whereas those inserted 8 and 16 h after the treatment did not differ from the controls. The data are related to the fluoride concentration in saliva at various periods after APF treatments.

Key concepts: Remineralisation, Fluoride, Saliva, Enamel paint, Dentistry, Tooth Remineralization, Chemistry, Phosphate

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