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A Versatile Particle Beam Interface for Coupling Hplc to Ion Trap, Quadrupole and Sector Mass Spectrometers

Colin S. Creaser, James W. Stygall

Open publisher page 3 citations

Abstract

A two-stage particle beam LC-MS interface, capable of being coupled to a quadrupole, sector or ion trap mass spectrometer, is described. The device has a modular design, allowing operating parameters to be easily optimized whilst in use. Successful coupling to a quadrupole ion trap mass spectrometer (ITMS) is achieved using a novel heated transfer line for analyte vaporization and scan routines which eliminate solvent ion effects.

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What this paper is about

A two-stage particle beam LC-MS interface, capable of being coupled to a quadrupole, sector or ion trap mass spectrometer, is described. The device has a modular design, allowing operating parameters to be easily optimized whilst in use. Successful coupling to a quadrupole ion trap mass spectrometer (ITMS) is achieved using a novel heated transfer line for analyte vaporization and scan routines which eliminate solvent ion effects.

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OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A two-stage particle beam LC-MS interface, capable of being coupled to a quadrupole, sector or ion trap mass spectrometer, is described. The device has a modular design, allowing operating parameters to be easily optimized whilst in use. Successful coupling to a quadrupole ion trap mass spectrometer (ITMS) is achieved using a novel heated transfer line for analyte vaporization and scan routines which eliminate solvent ion effects.

Key concepts: Ion trap, Quadrupole ion trap, Hybrid mass spectrometer, Mass spectrometry, Quadrupole mass analyzer, Quadrupole, Ion, Spectrometer

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A Versatile Particle Beam Interface for Coupling Hplc to Ion Trap, Quadrupole and Sector Mass Spectrometers — Research Paper | ScholarLens