Mapping of secondary somatosensory cortex activation induced by vibrational stimulation: an fMRI study
Joseph A. Maldjian, Allan Gottschalk, Rita Patel, Daniel Pincus, John A. Detre, David C. Alsop
Abstract
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Joseph A. Maldjian, Allan Gottschalk, Rita Patel, Daniel Pincus, John A. Detre, David C. Alsop
Abstract
Open-access reader
Sensory functional MRI was performed in seven normal volunteers at 1. 5 T using a vibratory stimulus applied to the pad of the first finger of the left hand. The data was normalized to a standard atlas, and individual and group statistical parametric maps were computed. Robust bilateral activation was demonstrated in the secondary somatosensory cortex (SII), indicating a bilateral representation of SII in humans. Greater maxima and activation volumes were achieved in contralateral SII as compared to SI. Sensory fMRI can provide a sensitive assay for probing the nature and function of SII in vivo.
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Sensory functional MRI was performed in seven normal volunteers at 1. 5 T using a vibratory stimulus applied to the pad of the first finger of the left hand. The data was normalized to a standard atlas, and individual and group statistical parametric maps were computed. Robust bilateral activation was demonstrated in the secondary somatosensory cortex (SII), indicating a bilateral representation of SII in humans. Greater maxima and activation volumes were achieved in contralateral SII as compared to SI. Sensory fMRI can provide a sensitive assay for probing the nature and function of SII in vivo.
Key concepts: Somatosensory system, Secondary somatosensory cortex, Statistical parametric mapping, Neuroscience, Sensory stimulation therapy, Stimulus (psychology), Sensory system, Stimulation